Daily Fried Food Consumption Increases the Risk of Heart Failure in US Male Physicians

Daily Fried Food Consumption Increases the Risk of Heart Failure in US Male Physicians

August 16, 2019 0 By Bertrand Dibbert


– Hello, my name is Jean-Pierre Després. I am the Vice Chair on the Council on Lifestyle and Cardiometabolic Health at the American Heart Association. And I am here with Dr. Luc Djoussé from Harvard who did a study, who is going to report here to me a study on the relationship between fried food consumption and health. So Dr. Djoussé, thank you for joining us. Could you tell us, in a nutshell, what the study is all about? What is it about? – Certainly we conducted
an observational study on fried food and the
risk of heart failure. The rationale behind the study is that, several studies have reported a positive association
between eating fried food and risk factor for heart failure including diabetes, high
blood pressure, heart attack. But the results have not been consistent. The Nurse’s Health Study, the
Health Professional’s study, show an increased risk
of consuming fried food with the risk of heart attack. But other studies, including
a large Spanish study did not show an association between fried food and heart attack. And as you know, heart
attack is a major risk factor for heart failure. So we wanted to know
whether we could assess the frequency of eating fried food in the Physician Health study and the risk of developing heart failure. – How many subjects were involved in this observational study? – Although the Physican Health study has about 30,000 male physician, we included after exclusion. . . missing data, 15,300 male subjects that were analyzed in this study. – And you had a follow-up
of how many years? – We have an average
follow-up of 10 years. – You report that relationship between consumption of fried food and obviously very regular consumption
of fried food is likely to be also a marker of a diet
of poor nutritional quality. Have you examined this
issue in your analysis? Yes we did, cuz that was our concern, that perhaps people eating french fry or fried chicken. It may be a marker of poor diet quality. But these, number one, they’re all male physician. But we assessed the overall diet quality using the Alternate Healthy Eating Index, which contained several metrics, including the number of servings of fruits and vegetable, whole grain, trans-fat, et cetera. And we broke down into quintile, meaning five equal groups of those 15,000. And the top three groups on that score are people with the best
overall diet quality. And we separate those from the bottom two quintile, which those were the poorest diet quality. And to our surprise, we saw that the result was strongest in the top three quintile, meaning the physician with the best overall diet quality
of frequent consumption of fried food was
associated with a high risk of developing heart failure in that group, suggesting that it is not an indication of poor diet quality. But it’s something other than that. For example, we know that fried foods can increase the energy density of food. If the person ingests more calorie than they need then the body will
store the excess calorie in terms of fat which could bring other risk factor, obesity, diabetes, high blood pressure. And this has been
independently demonstrated that frequency of fried food
consumption raised the risk of high blood pressure,
diabetes, and other risk factors. – So you think energy
density is a possibility. Is there also the possibility that obviously, that heat
exposure could alter the lipids? – That’s correct. That’s the second pathway. The second pathway is that when you heat the oil, you can increase the amount of trans-fat. And in our study we show
a positive correlation between the frequency of eating fried food and the amount of trans-fat in the diet, meaning more frequent
consumption of fried food led to more trans-fat. . . in the person. Second, we know that fried food can increase the amount of oxidized LDL cholesterol,
which is more atherogenic, meaning the progression of atherosclerosis could be accelerated by that process. We think there is some
viable potential mechanism by which eating fried food
could be detrimental to health. – Therefore, from a diet
prospective this is another thing that we need to have on radar screen in addition to paying
attention to diet quality, we should be careful
about overeating our food. – Absolutely. The good news from our study is that the risks do not double until you are eating
fried foods daily or more. When people were eating 1 to 3, the risk increase was only 24% When they were eating 4 to 6 per week, there was only 28% increased risk of heart failure. It’s only when they were
eating seven or more per week that we have the doubling increase of the rate of heart failure. Everything in moderation. – That’s right as it is often the case, take home message, in moderation please. – Thank you Dr. Djoussé – Thank you very much. (instrumental riff)